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Dany's RaaD Roundup

Vaccination as a Tool for Cancer Prevention

I was sifting through the Medscape articles I subscribe to and came across this article on cancer causing infections and the vaccines that have the potential to cut these cancers almost in half called Vaccination as a Tool for Cancer Prevention (read it here) written by Eric H. Raabe, MD, PhD; Julia M. Kim, MD, MPH and Miriam Alexander, MD, MPH. The full article is a very concise summary of the most common cancers that are caused by infections. I am posting the abstract to this article at the bottom of this post so you can get a preview.

Thanks to the Politico for the above image



Abstract: Infectious agents, such as viruses and bacteria, are the causes of several common cancers. Infection with the bacterium Helicobacter pylori predisposes to gastric cancer. Hepatitis B virus (HBV) and hepatitis C virus (HCV) are associated with liver cancer, and Epstein-Barr virus (EBV) is associated with lymphoma and nasopharyngeal cancer. Human papillomavirus (HPV) is a major cause of cervical, anal, penile, and oropharyngeal cancer. Together, infection-associated tumors make up nearly 20% of all cases of cancer worldwide, causing more than 2 million malignancies per year. Most of these cases occur in developing countries. Under normal circumstances, immune surveillance helps to keep many of these virus-associated cancers in check, but in immunocompromised persons, such as those with late-stage HIV infection, the incidence and aggressiveness of these cancers increase. HBV and HPV vaccines are effective and in use, and vaccines against other cancer-causing agents are in development. Because many virus-associated cancers occur in the developing world (such as EBV-associated Burkitt’s lymphoma in Africa and HBV-associated hepatocellular carcinoma [HCC] in Asia), the development and deployment of vaccines to prevent infection with HPV, HBV, HCV, and EBV can serve as effective preventative tools to reduce the burden of cancer morbidity and mortality worldwide.


August 31, 2010 8:58 pm - Posted by | health, medicine, science, technology

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